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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b300d44aa116db6558db112ee57c2d5100409d7b72b9c3934549d5d02f9c939b' 
  AND token = 'pzBKP0t19Q0Gyow3UCu3yWNSbQjgWFIgbSwaPxIUbWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}