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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765efbdb6de2e20aa717c240936407979c57b65111ea8d3616897b118f34706c' 
  AND token = 'Uic6qc0Fg3bx0reOT/kOFw9Sd5s6A/H1jxbC4VtR324=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}