SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e68262bdf3853edb872789c5cba2c551f64e99100ff8bffc40d909c86ac0a26f' 
  AND token = 'OeU6ndwvx2Io2GBop1UbPxs3VhyotpUQvV8nikjMBoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}