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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd61a2ed5f0c72d5fa6490e0298e79df091687b88a27a1e748ed1faccc8d83f69' 
  AND token = 'KMmK6AEJLWFfcx48XbY+9gtV2u3aa/s6ToiDVUwTBUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}