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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2b7378283c0c4c9bf9b277df04e4a183117e4cfefe263fc23bd36e8700a20b' 
  AND token = 'fwUKnCjFH8bVL6lzkk7QvtS+x3kw4ZV6b3N0vGlR2Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}