SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373e614702cced401a38be0df5ff35cd536369823d92f830002b1e2500f63177' 
  AND token = 'QizTvRTMgVlIUtv3cdMC8LSEuHVJJz8o3f0EytXq8H8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}