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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e198dc7355f8fcaf59e533b28b0f2801dc8ab40a470fa7ca4351a95dbc019981' 
  AND token = 'Z0pOq2Qn5fL5jyqB8TJbBdP8MXg0HLwF2WSsLgI8Ass=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}