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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd15495749aaf6c9a11dbb8e88f4c4f68c2bf4ebe4cc01bce1ab410abe2e489' 
  AND token = '0f0bQlVyFTCFt26Bklx+ZZZQs9nxF6nP/cutToo57rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}