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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae1cc53cb121c5eabbe08022cd93689df390f55c69fd0515dc94756346d09d72' 
  AND token = 'hQ9VY1bch/R2qOk3yviW8MEIM5T5TXXAfqSAWBpAgpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}