SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a1f945656e6403a7ceb6e3836d7e21c776d5fb1549c017d4416384896bd80a' 
  AND token = 'qnvg7/Xgu6MpIMC4oWCMAm+x6OPo9dxNfASQcWv/o2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}