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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '775253a8d5f9603621fb674fd7d383fcd78331a2d5cd2a295d9bb68a66f2f628' 
  AND token = 'P706qkA1agBvcHW1f939G6owb1SQs1vPHGDenZqXuZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}