SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44fdc5e47c2fe779d8b9a9d2479828771a01cd8bda6b0ee09a5bfdb1dcad965c' 
  AND token = 'q/XLJq0ejlibDV2MfYofBV7vW0TexpCHyzuqeA2FN94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}