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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f2b1eb22bd05e9523d22a0652673a2d327820122eb9fb71830e5f168c99981' 
  AND token = 'DRnTLEAsxHF1VhreQu6VrArkvXoyxSlctv7Acjn0bqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}