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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd48a2ddfce02bff34940faa34b2e22dbe73009d4df69320f9f6d01c31b71233' 
  AND token = 'DyMt49pS8DsZYf87gDmMNIryVcxl1JnQrc6wxUJ+NLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}