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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed2943c06cf681066f6262439db44b792e5744078fa74ee1090fc67f7b2f8f8' 
  AND token = '5lRqFJUk4c4VD+FFvLNlZwiCNtyvHefmx6DFU8nzzhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}