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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2fad41bc35c43e65a623b1c4894cf595ec8e453e39142bb189356723c56ae1' 
  AND token = 'erTOGer4Ywu9nrrWUw/myFruDFGKxgi4l294hKpyUNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}