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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d645c7ee88237d4b23fa8537dfe825b6a66bacbbcad782bd4a139e44b10f870' 
  AND token = 'Cls4tI4Z+yq8sBfBRCvvOCwM2x7CrAZvzmrgn+kslVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}