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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19afae4f6a3bd6821af9c8332ef0efcb5853bcb962679f18d82b87f0c8e0b651' 
  AND token = 'SiypvaLyhZJwGdyfcyganqQdSzUbO3W3TvnlrqRODv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}