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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5012c6b8c6f2f28b88105000ea5476291ff48215a42f2fa70c0a0547e7fa57' 
  AND token = 'rU4qH0FE9ta/mGcIWCp7WRGt4bUn1ugzmBRZkEV+duU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}