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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a15f1b9ce57b948baa098e5c42a211f5d9a29a2d1d2893975197b3d07de76b9' 
  AND token = 'eY2BMk9PPQSM7nvG2QkT4IWI+Uuw1CfV4BfDqrTIvb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}