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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1efc9944d84fc0749ce9a0c12e7f72c6078368817b2e36265aee5657adcecd3' 
  AND token = 'nPtMRXnAVYk0Ts0JzPUiosyzEqYMiaUyX65Uo/ShgNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}