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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af189e296eacc3440052f16bd897788c6226858a532a926545ad8b316f831f9' 
  AND token = 'meEfECcxFkcoM2zvJH8eB4/QgoEhZfSTb/DkIp4dPrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}