SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3edd28fbefecff6e916a5eb876001f84051c8dc60a79259c6a0abe4d382e2577' 
  AND token = '7s2DNXw7EZCUYYGCfL+wzCkL0KP6JkR7Jdnxi2aSg6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}