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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cd9301a15688031d255c21d0d73eb38170bb0b1ee0c58116f6d5ed713a6bdf' 
  AND token = 'uFiKbW9y9xfX7HL86rmRw/i8SfhSPapR7yBzA7FHOh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}