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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '873649e32aff4a7217330c6dc3dc82648586ae81f663cc94b3910d0a7418c9b2' 
  AND token = 'HBrql9J3dF1GJerSasdQChV2rYZi6F1wyLmQd3cHftw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}