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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ffa740a9032f0d1e5e59004e87d936d45a7d2b7b9b1a1a0bb09528636cbf27' 
  AND token = 'rwtXhzLAWWM3l2OpLKUefaJIm3M0X8EJWdk1t49+UPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}