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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4df635cb1227a20194bd29dabe842753c758e90233f49003fd0c3a73aee87b1' 
  AND token = 'VP/52A+x5/yRi3TcntEp16bkq2SbP00LOjwNoZIbOuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}