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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d1046e16d30819996861e8063a622fcf3326ad5fe9a3b09580c3248ad6ce0fd' 
  AND token = 'zY5WUsMJlL+78Zk6GMF+0Y8uzRKWQyKc0N1uhnYXhjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}