SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2776a9e367f634efb156640deffd8d9c5503389614fddec5671f4cd38a6aa720' 
  AND token = 'V7IF+2hYqlPmoPb08si40oEYv6+bWaY2z1KI0XNrtWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}