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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c2546542650c14962aec675ac80a7257d3ba9fd6a64f473211a1427e27c289b' 
  AND token = 'H2h2oGZ8kyVNPGVrqnzpbWr0V6vAJVm3vmpdVZwgAxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}