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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c7989ad88fa68d8b6f32d399faa51f1577d80d8c3fef33488ca4433ad3c065c' 
  AND token = 'yFt3+yXxTtPYvjg+9r6K+v9HHawkEc7ubPKag0XkBeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}