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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56a29d254258702afd1aac42641a00dabcec432d30d65c746242dda7d5f75e60' 
  AND token = '+ZJ/H/Detg7b8goGV0r/x3h3KBbveKu7oSZ7mHCc3+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}