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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c7a5432d087f223a151b36a9c8782e6141a69a7f3e5215e72177d6f1caaed5' 
  AND token = 'hlyqZhYJp2aRUvFyPym0zJh6RJTKq7I3FlfSsFQ3ljE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}