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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b652d8b5ca53b2a97892d241f8348f551f7c54b231642d32b967249608e9779f' 
  AND token = '27BDSXik2QCyzrQwh5geL+QdlcFD2txNusa+0Gl3Hyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}