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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01b20e71caa545621b2f3fcb8aa7e30a3c4146895f0d92651e5fb3faa7dca19' 
  AND token = 'PBwUTiWttXfuG8HSvyGWnQ4WbTdR2zAz7SNdC9esHwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}