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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657ef6dfe31a204b977bd6672199d1056e98e67fc41ac8845d8bb04d331a3518' 
  AND token = 'KgYOd3CoT3GbMh2SGWjoHBnatTJ4Qgr5Pbgt3dHDL3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}