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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe035d69f5f977127333b7de5c97c37a277ff4b83bb5532229fb3291e5b3227' 
  AND token = 'tfHewBm/jgzavHvE8B9mzLSW9lHcOrmiGaeFQUuicgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}