SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd425d3ae1331f5e4efc12c50ba320d003f26b371d1f4358ccda96267f4d516' 
  AND token = '3rtc3WWLJadW5QFlvqRTsrKRY5MH0EtaAJx7zDerBqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}