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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e33bacf2c45878c4bc6f9d9267700c897d3d1a16cecfad521ad6caa7d783680' 
  AND token = 'xer3kM4Fa7hdz/PCsR5KelMUDktk3oXj+lOf+bR2bmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}