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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1759eaa2e2a88265aaf0e620aa1de10d23c67840467c65fe6a479008ba14a52d' 
  AND token = 'cWOJ0YzKRqFeDwRMgthdZ7rWLMEMmTNI+t9ISDml/Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}