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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3b5dff6deef5e21888ce425f2928fa26b5b53db503f8c9ce5e9b1d36add241' 
  AND token = '0uPouxuIEAIuc9JBxcOYaqUYQSFDeUFBxGO2ePacYus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}