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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b7502a1c1bfe30ff211f09dba90c44148ae2d367becf7baa3625bcc2366f67' 
  AND token = 'qyeMId1Fp89RS14sbblP467zcLtOugbr4Q6c4IFZCK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}