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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa7f16b545e2c8ad3c0ab69225ffd0e086cc0edf8a846ee2c7f1c7fbdb59c7c' 
  AND token = 'N0xKjMzyrWZiLmthbhavSjmpd5ZntYXut9XzPIpk+mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}