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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8882f66135a48c3295e9b280967bc2e39ce12598c5447d1c9d72d0751f086d70' 
  AND token = 'kxNG6U/zIhxGwF0Gh+fX8uU2UgcU4z05vAUT3EDWmQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}