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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dec178a133af06819281e0bb2cc35f8093024bb6b385adad83ad102dcc2f43f2' 
  AND token = '4HHjVOKIaUYubbMMOPlz1pBZzrikx6NLGgFmMGqi5cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}