SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5b9de3f7f10b4c809c39505d4fc7658ae17c6ab310083562b491d6409cdf49' 
  AND token = 'EqKjdy4hTgoqkhrF6UnzyYFiLYlHMcD7pbYOxFf6o9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}