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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c1882cc847fa53e73bbf3859006f968c1190ac83ffd28bb43a7916bd78ee00' 
  AND token = 'LNk5psVzb+X+eyb3oiw74qBceErZH3bH0JGFf4GirdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}