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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4d74c2f7064c78bba21993545d69c47f3fa25631d7e08348a363367d63dafd' 
  AND token = 'TV/5DhHTcR+4bjvwMQfDIyai10Bjop2hjdYLyV88W4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}