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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d80a185fc3f182ac54928747011d677ee85896e2a2b121acd90ee6be8e22ee' 
  AND token = '0zyV3+3xoQxqrDMz1rK6OhfRfcvh8JUoOVXxqXU3rqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}