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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159cece1a61e7fea01bd8f6f40811b94a91d3ed5feb73467e7d373df4ad96153' 
  AND token = 'l4c0VWI6bewoEmdrzOIbqS+y8gXe0Ct9+shAWLrbNiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}